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KMID : 0360319920240050647
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Journal of Korean Cancer Research Association
1992 Volume.24 No. 5 p.647 ~ p.655
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CEA, CA19-9 and CA125 in Patients with Gastrointestinal Carcinoma
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Abstract
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Serum concentration of CEA, CA19-9 and CA125 were investigated to analyze the clinical significance and these tumor markers in 688 patients with gastrointestinal carcinoma, who were managed at the Departments of Surgery and Internal Medicine,
Keimyung
University Dongsan Hospital during 2 years from Nov. 1989 to Nov. 1991.
@ES The results were as following:
@EN 1) The positivity of the tumor marker was higher with CEA than CA 19-9 and CA125 in patients with gastric and colorectal carcinoma and with CA19-9 than CEA and CA125 in patients with pancreatic and biliary carcinoma.
2) Combined tumor marker studies were more sensitive than single testes and combination of CEA and CA19-9 showed higher sensitivity than other combinations for gastrointestinal carcinoma.
3) There were no significant correlations between the differentiation of the tumor and serum concentration of the tumor marker in patients with gastric and colorectal carcinoma, except mucinous type of gastric carcinoma, which showed
significantly
higher level of CA19-9.
4) CA 19-9 and CEA showed higher sensitivity than the others in patients with recurred gastric and colorectal carcinoma, respectively.
5) Mean serum level of CA19-9 was 18.3*15.8U/ml with positivity of 0% in patients with chronic pancreatitis in contrast to 640.1*507.8U/ml and 76% in patients with pancreatic carcinomas.
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KEYWORD
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